JIA is a condition characterized by joint inflammation and stiffness for more than 6 weeks in a child of 16 years or younger. Inflammation causes redness, swelling, warmth, and soreness in the joints, although many children with JIA do not complain of joint pain. Any joint can be affected and inflammation may limit the mobility of affected joints. In polyarticular-course JIA, five or more joints are affected. The small joints, such as those in the hands and feet, are most commonly involved, but JIA may also affect large joints.
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